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Cytology of Pleural, Pericardial and Peritoneal Cavity Effusions

EFFUSIONS - HEMATOLOGIC MALIGNANCIES

Cells are discohesive because these are not true epithelial cells. Nuclei are large and vesicular and may include a pseudo-inclusion, which is in reality cytoplasm indenting the nuclear membrane. Pigmentation of the cytoplasm is often but not always present. Immunohistochemistry can confirm the identity of these cells either on ThinPrep slides or cell block material.

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